Aulton's Pharmaceutics,

Edition 6 The Design and Manufacture of Medicines

Editors: Edited by Kevin M.G. Taylor, BPharm PhD FRPharmS and Michael E. Aulton, BPharm, PhD, FAAPS, FSP, FRPharmS

Publication Date: 14 May 2021

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One of the world’s best-known texts on pharmaceutics, Aulton's Pharmaceutics offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees.

Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery.

All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course.

Key Features

Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation
Designed and written for newcomers to the design and manufacture of dosage forms
Relevant pharmaceutical science covered throughout
Includes the science of formulation and drug delivery
Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines
Key points boxes throughout
Over 400 online multiple-choice questions

About the author

Edited by Kevin M.G. Taylor, BPharm PhD FRPharmS, Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London, UK and Michael E. Aulton, BPharm, PhD, FAAPS, FSP, FRPharmS, Emeritus Professor, De Montfort University, Leicester, UK

1. Design of dosage forms
Peter York
2. Dissolution and solubility
Michael E. Aulton
3. Properties of solutions
Michael E. Aulton
4. Surfaces and interfaces
Graham Buckton
5. Disperse systems
David Attwood
6. Rheology
Christopher Marriott
7. Kinetics
Gareth R. Williams and John P. Malkinson
8. Solid-state properties
Graham Buckton
9. Particle size analysis
Kevin M.G. Taylor
10. Particle size reduction and size separation
Michael E. Aulton
11. Mixing
Andrew M. Twitchell
12. Powder flow
Michael E. Aulton
13. Fundamentals of microbiology
Lara-Marie Barnes and Geoffrey W. Hanlon
14. Pharmaceutical applications of microbiological techniques
Lara-Marie Barnes and Norman A. Hodges
15. Action of physical and chemical agents
on microorganisms
Lara-Marie Barnes, Geoffrey W. Hanlon and Norman A. Hodges
16. Principles of sterilization
Susannah E. Walsh, Katie Laird and Jean-Yves Maillard
17. Sterilization in practice
Jean-Yves Maillard, Katie Laird and Susannah E. Walsh
18. Introduction to biopharmaceutics
Marianne Ashford and Kevin M.G. Taylor
19. Gastrointestinal tract e physiology and drug absorption
Marianne Ashford and Kevin M.G. Taylor
20. Bioavailability e physicochemical, dosage form and formulation factors
Marianne Ashford, Kevin M.G. Taylor and Hala M. Fadda
21. Assessment of biopharmaceutical properties
Marianne Ashford and Kevin M.G. Taylor
22. Dosage regimens
Soraya Dhillon and Nkiruka Umaru
23. Pharmaceutical preformulation
Simon Gaisford
24. Solutions
Sudaxshina Murdan
25. Clarification
Andrew M. Twitchell
26. Suspensions
Susan A. Barker
27. Emulsions and creams
Gillian M. Eccleston
28. Ointments, pastes, gels, cutaneous patches and topical sprays
Majella E. Lane
29. Powders, granules and granulation
Michael E. Aulton
30. Drying
Michael E. Aulton and Satyanarayana Somavarapu
31. Tablets and compaction
Göran Alderborn and Göran Frenning
32. Modified-release oral drug delivery
Emma L. McConnell, Christine M. Madla and Abdul W. Basit
33. Coating of tablets and multiparticulates
Stuart C. Porter
34. Continuous manufacturing of tablets
Aktham Aburub and Hala M. Fadda
35. Hard capsules
Brian E. Jones
36. Soft capsules
Stephen Tindal
37. Dissolution testing of solid dosage forms
Ana Cristina Freire, Francesca K.H. Gavins and
Abdul W. Basit
38. Parenteral drug delivery
Robert Lowe
39. Pulmonary drug delivery
Kevin M.G. Taylor
40. Nasal drug delivery
Gary P. Martin and Alison B. Lansley
41. Ocular drug delivery
Hala Fadda, Ashkan Khalili, Peng Tee Khaw and Steve Brocchini
42. Otic drug delivery
Xu Liu, Hugh Smyth and Feng Zhang
43. Topical and transdermal drug delivery
Adrian C. Williams
44. Rectal and vaginal drug delivery
Kalliopi Dodou
45. Preparation and delivery of biopharmaceuticals
Ijeoma F. Uchegbu and Andreas G. Schätzlein
46. Pharmaceutical nanotechnology and nanomedicines
Yvonne Perrie
47. Radiopharmaceuticals
Neil Hartman and Margaret Cooper
48. The formulation and manufacture of plant medicines
G. Brian Lockwood
49. Design and administration of medicines for paediatric and geriatric patients
Catherine Tuleu, Mine Orlu and David Wright
50. Packaging
Sudaxshina Murdan
51. Chemical stability in dosage forms
Andrew R. Barnes and Mark Santillo
52. Microbial contamination, spoilage and preservation of medicines
Norman A. Hodges and Lara-Marie Barnes
53. Product stability and stability testing
Paul Marshall
54. Pharmaceutical quality: the application of pharmaceutics in medicines regulation
Kevin M.G. Taylor, Majella E. Lane and Khalid A. Sheikh
Self-assessment questions
Sudaxshina Murdan

ISBN: 9780702081545

Page Count: 968

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