Microbiology & Immunology Case Reports,

Edition 1

Editors: Edited by Ken S. Rosenthal, PhD, Emily Blodget, MD, Susan Butler-Wu, PhD, Wendy Gould, MD, Minto Porter, MD, Raj Dasgupta, MD, FACP, FCCP, FAASM, Raj Dasgupta, MD, FACP, FCCP, FAASM and Michele Koolaee, MD

Publication Date: 20 Jul 2026

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Microbiology and Immunology Case Reports: Beyond the Pearls is a case-based reference that covers the key material essential for USMLE and exam preparation. Focusing on the practical information you need to know, it teaches how to analyze a clinical vignette, sharpening your clinical decision-making skills and helping you formulate an evidence-based approach to realistic patient scenarios.

Key Features

Covers core, high-yield content on microbiology and immunology in a practical, concise, easy-to-read manner
Features case scenarios, clinical pearls, tables, imaging, microscopic and gross illustrations, as well as Beyond the Pearls tips and secrets (all evidence-based with references) that provide deep coverage of core material
Teaches how to learn with a patient-focused, clinical approach
Includes questions throughout the case that put you in the physician’s place and demonstrate the decision making that is needed both in the hospital and on exams
Cases have been carefully chosen and cover scenarios and questions frequently encountered on the USMLE, shelf exams, and clinical practice, integrating both basic science and clinical pearls
Written and edited by experienced teachers and clinicians; each case has been reviewed by board certified attending/practicing physicians and basic scientists
Case Reports: Beyond the Pearls titles are ideal for all medical students, especially those in case-based, problem-based, or integrated courses, and during clinical rotations
An eBook version is included with purchase. The eBook allows you to access all of the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud

About the author

Edited by Ken S. Rosenthal, PhD, Adjunct Professor Infectious Diseases University of Georgia College of Veterinary Medicine; Professor of Immunology Augusta University, University of Georgia Medical Partnership Athens, Georgia; Emeritus Professor Northeastern Ohio Medical University Rootstown, Ohio; Emily Blodget, MD, Clinical Associate Professor of Medicine (Clinician Educator), ACGME Infectious Diseases Fellowship Program Director, Co-Interim Chief for the Division of Infectious Diseases, School, Keck School of Medicine of USC, USA; Susan Butler-Wu, PhD, Director of Clinical Microbiology, LAC+USC Medical Center; Associate Professor of Clinical Pathology; Keck School of Medicine of USC, Los Angeles, CA, USA; Wendy Gould, MD, Attending Physician, Allergy and Clinical Immunology, Allergy and Immunology, Sussman Allergy, Toronto, Ontario, Canada; Minto Porter, MD, Allergy, Asthma, and Immunology, Essentia Health, Brainerd, USA; Raj Dasgupta, MD, FACP, FCCP, FAASM, Associate Professor of Clinical Medicine, University of California, Riverside School of Medicine; Associate Program Director of Internal Medicine Residency, Huntington Health, Pasadena, California, USA; Raj Dasgupta, MD, FACP, FCCP, FAASM, Associate Professor of Clinical Medicine, University of California, Riverside School of Medicine; Associate Program Director of Internal Medicine Residency, Huntington Health, Pasadena, California, USA and Michele Koolaee, MD, Assistant Professor of Clinical Medicine, Division of Rheumatology, Keck School of Medicine of the University of Southern California, Los Angeles, California

Introduction- Microbiology
Introduction- Immunology
Microbiology
Bacteria
1. A 28-year-old female with fever and abdominal pain
2. A 25-year-old female with intermittent fever and abdominal pain
3. A 48-year-old female with abdominal cramping and painful diarrhea
4. A 72-year-old female with diarrhea after recent hospitalization
5. A 49-year-old female with sore throat and fever
6. A 68-year-old male with fever, cough and worsening dyspnea
7. A 35 year old male presents with a seizure
8. A 21-year-old male with pharyngitis
9. A 70-year-old female with fevers and chills
10. A 56-year-old male with fevers, weakness and a rash
11. A 62-year-old female with flank pain and fevers
12. A 54-year old homeless male with fevers, chills and shortness of breath
13. A 43-year-old female presents to the urgent care with a 3-day history of sore throat, and pain when swallowing
14. An 83-year-old female with generalized weakness, fever and altered mentation
15. A 42-year-old man with low back pain
16. A 20-year-old male with penile discharge
17. A 57-year-old with history of chronic lymphocytic leukemia presenting with 2 weeks of fever, cough and dyspnea
18. A 23-year-old female with hemoptysis
19. A 66-year-old female with two years of productive cough, dyspnea, and malaise
Virus
20. An 11 month-old girl with a rash
21. A 35-year-old female with vomiting and diarrhea after a cruise
22. A 39-year-old male with right upper quadrant pain and hematochezia
23. A 48-year-old male with non-productive cough, dyspnea, and loss of smell
24. A 30-year-old female with malaise, cough, and myalgias
25. A 42 -year-old female with odynophagia
26. A 16-year old female with sore throat
27. A 34-year old female with diarrhea
28. A 48-year-old male with sudden onset of fever, headache, and confusion
29. A 38-year-old HIV patient with various non-specific symptoms
Fungus
30. A 57-year -old female with cough and weight loss
31. A 55-year-old female with lung transplant now with cough, fever, and pleuritic chest pain
32. A 21-year old male with hemoptysis
33. A 72-year-old male with a painful knee
Parasite
34. A 45-year-old male with prolonged diarrhea
35. A 70-year-old female with abdominal pain
36. A 40-year-old immunocompromized male with ring-enhancing lesions
37. A 35-year-old male returning from travel with fever and headache
38. A 45-year old male with heart failure and cardiomyopathy
Immunology
39. A 6-year-old boy with fever, cough, and shortness of breath
40. A 20-month-old girl with recurrent infections
41. A 25-year-old female with a diffuse, itchy rash, fatigue and joint pain
42. A 7-month-old boy presents with chronic diarrhea and failure to thrive
43. A 24-year-old female presents with chronic rhinitis, sinus congestion and recurring sinusitis
44. A 50-year-old male establishing care
45. A 4-day-old boy presents with lethargy, poor feeding and craniofacial abnormalities
46. A 4-month-old boy with bloody diarrhea and eczema
47. A 33-year-old pregnant female presents with fever, cough and myalgia
48. A 66-year-old male is found by paramedics with hives, hypotension and loss of consciousness
49. A 6-year-old girl with wheezing, lip swelling and vomiting
50. A 29-year-old male with hemoptysis
51. A 12-year-old boy with fever, arthralgia, and rash
52. A 14-year old boy with weeping pruritic lesions on lower extremities
53. A 7-Year-Old Boy With Arthralgias, Abdominal Pain, and Palpable Purpura
54. A 67-year-old male that has malaise and fever after a kidney transplant
55. A 4-month-old infant with a history of severe combined immunodeficiency who underwent allogenic stem cell transplant and presents with pruritic morbilliform rash and diarrhea56. A 4-year-old boy presents with persistent rash and chronic pruritus
57. A 4-year-old boy with burning sensation in the chest and abdominal pain
58. A 42-year-old female presents to the Emergency Department with generalized pruritus